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Force-induced unravelling of DNA origami

Abstract:

The mechanical properties of DNA nanostructures are of widespread interest as applications that exploit their stability under constant or intermittent external forces become increasingly common. We explore the force response of DNA origami in comprehensive detail by combining AFM single molecule force spectroscopy experiments with simulations using oxDNA, a coarse-grained model of DNA at the nucleotide level, to study the unravelling of an iconic origami system: the Rothemund tile. We contras...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1021/acsnano.8b01844

Authors


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ORCID:
0000-0002-2598-9711
Sajfutdinow, M More by this author
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ORCID:
0000-0002-0040-0173
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Funding agency for:
Rovigatti, L
Publisher:
American Chemical Society Publisher's website
Journal:
ACS Nano Journal website
Volume:
12
Issue:
7
Pages:
6734-6747
Publication date:
2018-05-31
Acceptance date:
2018-05-31
DOI:
EISSN:
1936-086X
ISSN:
1936-0851
Pubs id:
pubs:854873
URN:
uri:4f7af895-25c9-4fb3-82a9-36d9eecbf23b
UUID:
uuid:4f7af895-25c9-4fb3-82a9-36d9eecbf23b
Local pid:
pubs:854873

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