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Expression and immune function of tenascin-C.

Abstract:

Our immune system is designed to protect us from danger. Upon pathogen invasion and tissue injury, activation of both innate and adaptive immunity enables us to combat infection and to repair tissue damage. Tenascin-C is a large, extracellular matrix glycoprotein that has a very tightly controlled pattern of expression. Little or no tenascin-C is expressed in most healthy adult tissues; however, it is rapidly and transiently induced at sites of tissue injury and infection. Persistent tenascin...

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Publication status:
Published

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Authors


Udalova, IA More by this author
Ruhmann, M More by this author
Thomson, SJ More by this author
Midwood, KS More by this author
Journal:
Critical reviews in immunology
Volume:
31
Issue:
2
Pages:
115-145
Publication date:
2011
DOI:
ISSN:
1040-8401
URN:
uuid:4f6ca387-3f31-466a-a34a-0d6a03d3d97b
Source identifiers:
225998
Local pid:
pubs:225998

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