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Journal article

Biology of prostate-specific antigen

Abstract:

The human kallikrein (hk) family, located on chromosome 19, encodes prostate-specific antigen (PSA [or hK3]), hK2, hK4, and hK15 (prostin), as well as other serine proteases. Although PSA has been used in the detection of prostate cancer for several years, much remains unknown about its function and forms. The regulatory mechanisms of PSA are vital to its understanding. A particular mechanism by which PSA forms complexes with either α 1-antichymotrypsin or α2-macroglobulin may provide importa...

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Journal:
Urology
Volume:
62
Issue:
5 SUPPL. 1
Pages:
27-33
Publication date:
2003-11-05
DOI:
ISSN:
0090-4295
URN:
uuid:4eef1578-049d-427d-9a39-c2ba261bb588
Source identifiers:
367554
Local pid:
pubs:367554
Language:
English

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