Journal article
Studying neuroanatomy using MRI
- Abstract:
- The study of neuroanatomy using imaging enables key insights into how our brains function, are shaped by genes and environment, and change with development, aging and disease. Developments in MRI acquisition, image processing and data modeling have been key to these advances. However, MRI provides an indirect measurement of the biological signals we aim to investigate. Thus, artifacts and key questions of correct interpretation can confound the readouts provided by anatomical MRI. In this review we provide an overview of the methods for measuring macro- and mesoscopic structure and for inferring microstructural properties; we also describe key artifacts and confounds that can lead to incorrect conclusions. Ultimately, we believe that, although methods need to improve and caution is required in interpretation, structural MRI continues to have great promise in furthering our understanding of how the brain works.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
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- Files:
-
-
(Preview, Accepted manuscript, pdf, 7.3MB, Terms of use)
-
- Publisher copy:
- 10.1038/nn.4501
Authors
- Publisher:
- Springer Nature
- Journal:
- Nature Neuroscience More from this journal
- Volume:
- 20
- Issue:
- 3
- Pages:
- 314-326
- Publication date:
- 2017-02-23
- Acceptance date:
- 2017-01-13
- DOI:
- EISSN:
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1546-1726
- ISSN:
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1097-6256
- Language:
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English
- Keywords:
- Pubs id:
-
pubs:681859
- UUID:
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uuid:4eacde31-96bd-49be-bc0a-771d0ae06956
- Local pid:
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pubs:681859
- Source identifiers:
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681859
- Deposit date:
-
2017-03-01
- ARK identifier:
Terms of use
- Copyright holder:
- Lerch et al
- Copyright date:
- 2017
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from Springer Nature at: https://doi.org/10.1038/nn.4501
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