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Pre-clinical evaluation of antiviral activity of nitazoxanide against SARS-CoV-2

Abstract:

Background
To address the emergence of SARS-CoV-2, multiple clinical trials in humans were rapidly started, including those involving an oral treatment by nitazoxanide, despite no or limited pre-clinical evidence of antiviral efficacy.

Methods
In this work, we present a complete pre-clinical evaluation of the antiviral activity of nitazoxanide against SARS-CoV-2.

Findings
First, we confirmed the in vit...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.ebiom.2022.104148

Authors


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Role:
Author
ORCID:
0000-0003-2318-9662
More by this author
Role:
Author
ORCID:
0000-0002-4734-2249
Publisher:
Elsevier
Journal:
EBioMedicine More from this journal
Volume:
82
Article number:
104148
Publication date:
2022-07-10
Acceptance date:
2022-06-22
DOI:
EISSN:
2352-3964
Pmid:
35834886
Language:
English
Keywords:
Pubs id:
1268223
Local pid:
pubs:1268223
Deposit date:
2023-01-10

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