Journal article

Transcriptomic signatures induced by the Ebola virus vaccine rVSVΔG-ZEBOV-GP in adult cohorts in Europe, Africa, and North America: a molecular biomarker study

Abstract:: Background A recombinant vesicular stomatitis virus vector expressing the Zaire Ebola virus glycoprotein (rVSVΔG-ZEBOV-GP) vaccine has been reported as safe, immunogenic, and highly protective in a ring vaccination trial. We aimed to identify transcriptomic immune response biomarker signatures induced by vaccination and associated signatures with its immunogenicity and reactogenicity to better understand the potential mechanisms of action of the vaccine. Methods 354 healthy adult volunteer...
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Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Vianello, E., Gonzalez-Dias, P., van Veen, S., Engele, C. G., Quinten, E., Monath, T. P., Medaglini, D., Agnandij, S. T., Ahmed, R., Anderson, J., Auderset, F., Bejon, P., Borgianni, L., Brosnahan, J., Ciabattini, A., Engler, O., Haks, M. C., Harandi, A. M., Heppner, D. G., … Agnandji, S. T. (2021). Transcriptomic signatures induced by the Ebola virus vaccine rVSVΔG-ZEBOV-GP in adult cohorts in Europe, Africa, and North America: a molecular biomarker study. Lancet Microbe, 3(2), e113–e123.

MLA Style

Vianello, E, et al. “Transcriptomic Signatures Induced by the Ebola Virus Vaccine RVSVΔG-ZEBOV-GP in Adult Cohorts in Europe, Africa, and North America: a Molecular Biomarker Study.” Lancet Microbe, vol. 3, no. 2, 2021, pp. e113–e123.

Chicago Style

Vianello, E, P Gonzalez-Dias, S van Veen, et al. 2021. “Transcriptomic Signatures Induced by the Ebola Virus Vaccine RVSVΔG-ZEBOV-GP in Adult Cohorts in Europe, Africa, and North America: a Molecular Biomarker Study.” Lancet Microbe 3 (2): e113–e123.
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Files:: Vianello_et_al_2021_transcriptomic_signatures_induced.pdf

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Publisher copy:: 10.1016/S2666-5247(21)00235-4

Authors

+ Vianello, E More by this author

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+ Gonzalez-Dias, P More by this author

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+ van Veen, S More by this author

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+ Engele, CG More by this author

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+ Quinten, E More by this author

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Publisher:: Elsevier
Journal:: Lancet Microbe More from this journal
Volume:: 3
Issue:: 2
Pages:: e113-e123
Publication date:: 2021-12-06
DOI:: 10.1016/S2666-5247(21)00235-4
EISSN:: 2666-5247

Language:: English
Keywords:: FFR
Pubs id:: 1257047
Local pid:: pubs:1257047
Deposit date:: 2022-06-10
ARK identifier:: ark:/29072/ora_4e6b8b142b184b9a81a3fd0aa99bbac0

Terms of use

Copyright holder:: Vianello et al.
Copyright date:: 2022
Rights statement:: © 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.

Licence:: CC Attribution (CC BY)

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