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Journal article : Review

Chimeric antigen receptor (CAR) T‐cell therapy for people with relapsed or refractory diffuse large B‐cell lymphoma

Abstract:

Background

Diffuse large B‐cell lymphoma (DLBCL) is an aggressive cancer of the lymphatic system. About 30% to 40% of people with DLBCL experience relapse and 10% are refractory to first‐line treatment usually consisting of R‐CHOP chemotherapy. Of those eligible for second‐line treatment, commonly consisting of salvage chemotherapy followed by autologous stem‐cell transplantation (ASCT), around 50% experience relapse. With a median overall survival of less than six to ... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1002/14651858.cd013365.pub2

Authors



Publisher:
Cochrane Collaboration
Journal:
Cochrane Database of Systematic Reviews More from this journal
Volume:
2021
Issue:
9
Article number:
CD013365
Place of publication:
England
Publication date:
2021-09-13
DOI:
EISSN:
1469-493X
Pmid:
34515338


Language:
English
Keywords:
Subtype:
Review
Pubs id:
1198306
Local pid:
pubs:1198306
Deposit date:
2021-10-12

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