Journal article : Review
Chimeric antigen receptor (CAR) T‐cell therapy for people with relapsed or refractory diffuse large B‐cell lymphoma
- Abstract:
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Background
Diffuse large B‐cell lymphoma (DLBCL) is an aggressive cancer of the lymphatic system. About 30% to 40% of people with DLBCL experience relapse and 10% are refractory to first‐line treatment usually consisting of R‐CHOP chemotherapy. Of those eligible for second‐line treatment, commonly consisting of salvage chemotherapy followed by autologous stem‐cell transplantation (ASCT), around 50% experience relapse. With a median overall survival of less than six to ... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 1.7MB, Terms of use)
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- Publisher copy:
- 10.1002/14651858.cd013365.pub2
Authors
- Publisher:
- Cochrane Collaboration
- Journal:
- Cochrane Database of Systematic Reviews More from this journal
- Volume:
- 2021
- Issue:
- 9
- Article number:
- CD013365
- Place of publication:
- England
- Publication date:
- 2021-09-13
- DOI:
- EISSN:
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1469-493X
- Pmid:
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34515338
- Language:
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English
- Keywords:
- Subtype:
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Review
- Pubs id:
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1198306
- Local pid:
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pubs:1198306
- Deposit date:
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2021-10-12
Terms of use
- Copyright holder:
- Cochrane Collaboration
- Copyright date:
- 2021
- Rights statement:
- Copyright © 2021 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
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