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EM∩IM: software for relating ion mobility mass spectrometry and electron microscopy data

Abstract:
We present EM∩IM, software that allows the calculation of collision cross-sections from electron density maps obtained for example by means of transmission electron microscopy. This allows the assessment of structures other than those described by atomic coordinates with ion mobility mass spectrometry data, and provides a new means for contouring and validating electron density maps. EM∩IM thereby facilitates the use of data obtained in the gas phase within structural biology studies employing diverse experimental methodologies.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1039/c5an01636c

Authors

More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry; Physical & Theoretical Chem
Role:
Author
ORCID:
0000-0003-4672-471X
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Physical & Theoretical Chem
Oxford college:
University College
Role:
Author
ORCID:
0000-0002-1507-3742


Publisher:
Royal Society of Chemistry
Journal:
Analyst More from this journal
Volume:
141
Issue:
1
Pages:
70-75
Publication date:
2015-11-23
Acceptance date:
2015-11-23
DOI:
EISSN:
1364-5528
ISSN:
0003-2654
Pmid:
26616427


Language:
English
Keywords:
Pubs id:
pubs:589077
UUID:
uuid:4d88da62-7ffd-4674-90ba-f222160a44ca
Local pid:
pubs:589077
Source identifiers:
589077
Deposit date:
2018-03-18
ARK identifier:

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