Journal article icon

Journal article

Ethyl beta-carboline carboxylate lowers seizure threshold and antagonizes flurazepam-induced sedation in rats.

Abstract:

The mammalian central nervous system possesses specific high-affinity binding sites for the benzodiazepines and considerable evidence suggests that these binding sites are the pharmacological receptors through which these compounds act. Recently, ethyl beta-carboline-3-carboxylate (beta-CCE) has been identified in both human urine and rat brain. beta-CCE may be closely related to the endogenous ligand for the benzodiazepine receptor--it shows an affinity for the receptor of the same order as ...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1038/290054a0

Authors


Journal:
Nature
Volume:
290
Issue:
5801
Pages:
54-55
Publication date:
1981-03-05
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
URN:
uuid:4d65a671-bd28-4167-9986-736ca8ca431f
Source identifiers:
185972
Local pid:
pubs:185972

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP