Journal article
ACSL3 regulates lipid droplet biogenesis and ferroptosis sensitivity in clear cell renal cell carcinoma
- Abstract:
- ACSL3 regulates the accumulation of lipid droplets in ccRCC and is essential for tumor growth. In addition, ACSL3 also modulates ferroptosis sensitivity in a manner dependent on the composition of exogenous fatty acids. Both functions of ACSL3 could be exploited for ccRCC therapy.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 2.6MB, Terms of use)
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- Publisher copy:
- 10.1186/s40170-022-00290-z
Authors
- Publisher:
- BioMed Central
- Journal:
- Cancer and Metabolism More from this journal
- Volume:
- 10
- Issue:
- 1
- Pages:
- 14-14
- Article number:
- 14
- Publication date:
- 2022-10-03
- DOI:
- EISSN:
-
2049-3002
- ISSN:
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2049-3002
- Language:
-
English
- Keywords:
- Pubs id:
-
1281432
- Local pid:
-
pubs:1281432
- Source identifiers:
-
W4300960565
- Deposit date:
-
2026-04-28
- ARK identifier:
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Terms of use
- Copyright date:
- 2022
- Licence:
- CC Attribution (CC BY)
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