Journal article
Evaluation of an empiric risk screening score to identify acute and early HIV-1 infection among MSM in Coastal Kenya
- Abstract:
- We evaluated the University of North Carolina-Malawi Risk Screening Score (UMRSS) for detection of acute and early HIV-1 infection (AEHI) in a cohort of Kenyan MSM with approximately 8% annual HIV-1 incidence. Three components of the UMRSS (fever, diarrhea, and discordant rapid HIV tests) were also independent predictors of AEHI in our cohort. The predictive ability (area under the receiver operating characteristic curve, AUC) of the UMRSS was 0.79. A cohort-derived risk score consisting of six characteristics (fever, diarrhea, discordant rapid HIV tests, fatigue, age <30 years, and symptomatic sexually transmitted disease) had a higher AUC of 0.85. Screening for AEHI will have substantial transmission prevention benefits.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 331.7KB, Terms of use)
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(Preview, Supplementary materials, pdf, 63.3KB, Terms of use)
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- Publisher copy:
- 10.1097/QAD.0b013e3283629095
Authors
+ United States Agency for International Development
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- Funder identifier:
- https://ror.org/01n6e6j62
- Publisher:
- Lippincott, Williams and Wilkins
- Journal:
- AIDS More from this journal
- Volume:
- 27
- Issue:
- 13
- Pages:
- 1-4
- Publication date:
- 2013-08-01
- Acceptance date:
- 2013-04-24
- DOI:
- EISSN:
-
1473-5571
- ISSN:
-
1473-5571
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:411106
- UUID:
-
uuid:4d1961bd-2953-4338-8770-e741125ff297
- Local pid:
-
pubs:411106
- Source identifiers:
-
411106
- Deposit date:
-
2013-11-17
- ARK identifier:
Terms of use
- Copyright holder:
- Lippincott Williams and Wilkins
- Copyright date:
- 2013
- Rights statement:
- Copyright © Lippincott Williams and Wilkins. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivitives 3.0 License, where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially. http://creativecommons.org/licenses/by-nc-nd/3.0.
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