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Journal article

Antibodies against hypocretin receptor 2 are rare in narcolepsy

Abstract:

Study Objectives

Recently, antibodies to the hypocretin receptor 2 (HCRTR2-Abs) were reported in a high proportion of narcolepsy patients who developed the disease following Pandemrix® vaccination. We tested a group of narcolepsy patients for the HCRTR2-Abs using a newly established cell-based assay.

Methods

Sera from 50 narcolepsy type 1 (NT1) and 11 narcolepsy type 2 (NT2) patients, 22 patients with other sleep disorders, 15 healthy controls, and 93 disease cont...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1093/sleep/zsw056

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
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European Academy of Neurology More from this funder
Publisher:
Oxford University Press Publisher's website
Journal:
Sleep Journal website
Volume:
40
Issue:
2
Pages:
zsw056
Publication date:
2016-12-10
Acceptance date:
2016-10-01
DOI:
EISSN:
1550-9109
ISSN:
0161-8105
Pubs id:
pubs:686140
URN:
uri:4d158dc4-5882-453c-84cd-cdf86ba6ca7a
UUID:
uuid:4d158dc4-5882-453c-84cd-cdf86ba6ca7a
Local pid:
pubs:686140

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