Journal article icon

Journal article

Regulation of ligands for the activating receptor NKG2D.

Abstract:

The outcome of an encounter between a cytotoxic cell and a potential target cell depends on the balance of signals from inhibitory and activating receptors. Natural Killer group 2D (NKG2D) has recently emerged as a major activating receptor on T lymphocytes and natural killer cells. In both humans and mice, multiple different genes encode ligands for NKG2D, and these ligands are non-classical major histocompatibility complex class I molecules. The NKG2D-ligand interaction triggers an activati...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Mistry, AR More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, CCMP
Journal:
Immunology
Volume:
121
Issue:
4
Pages:
439-447
Publication date:
2007-08-05
DOI:
EISSN:
1365-2567
ISSN:
0019-2805
URN:
uuid:4cd6c97a-c546-45d6-9d9c-7ef815fb1289
Source identifiers:
18203
Local pid:
pubs:18203

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP