Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation

Journal article

In the version of this article originally published, in the Methods section "Mouse LPS ALI model," the second sentence needed clarification of wording and dosage (mg kg–1, not mg g–1) and has been amended to read "Mice were treated daily (days 1–4 post-LPS), by subcutaneous injection, with PBS or 0.75 mg kg–1 of porcine CSF-1 fused to the Fc region of porcine IgG1a (generated by David Hume), prior to cull on day 5" in the HTML and PDF versions of the article

Authors: Mirchandani, AS; Jenkins, SJ; Bain, CC; Sanchez-Garcia, MA; Lawson, H

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: Nature Research
• Journal: Nature Immunology
• Volume: 23
• Issue: 6
• Pages: 927-939
• Publication date: 2022-05-27
• DOI: 10.1038/s41590-022-01216-z
• EISSN: 1529-2916
• ISSN: 1529-2908
• Language: English
• Keywords: Inflammation; Immunology; Hypoxia (environmental); Medicine; Immune system; Diffuse alveolar damage; Acute respiratory distress; Lung; ARDS; Internal medicine; Hypoxemia; Chemistry; Monocyte