Journal article
Asymmetric synthesis of secondary benzylic alcohols via arene chromium tricarbonyl complexes
- Abstract:
- (Aryl aldehyde)- and (aryl ketone)-chromium tricarbonyl complexes ortho-substituted with the chiral auxiliary O-methyl-N-(α-methylbenzyl)hydroxylamine undergo diastereoselective addition of Grignard reagents and Super-Hydride®, respectively, to give the corresponding secondary alcohols in high diastereoisomeric purity. These compounds may be easily decomplexed and deprotected to give the corresponding enantiopure amino alcohols.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Accepted manuscript, pdf, 244.2KB, Terms of use)
-
- Publisher copy:
- 10.1016/j.tet.2018.08.033
Authors
- Publisher:
- Elsevier
- Journal:
- Tetrahedron More from this journal
- Volume:
- 74
- Issue:
- 40
- Pages:
- 5965-5973
- Publication date:
- 2018-08-25
- Acceptance date:
- 2018-08-23
- DOI:
- ISSN:
-
0040-4020
- Keywords:
- Pubs id:
-
pubs:911136
- UUID:
-
uuid:4c92d276-1e5a-43b5-9b96-ae5515db2399
- Local pid:
-
pubs:911136
- Source identifiers:
-
911136
- Deposit date:
-
2018-08-30
Terms of use
- Copyright holder:
- Elsevier Ltd
- Copyright date:
- 2018
- Notes:
- Copyright © 2018 Elsevier Ltd. This is the accepted manuscript version of the article. The final version is available online from Elsevier at: https://doi.org/10.1016/j.tet.2018.08.033
If you are the owner of this record, you can report an update to it here: Report update to this record