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Cardiovascular fitness as a risk factor for amyotrophic lateral sclerosis: Indirect evidence from record linkage study

Abstract:

Background: Amyotrophic lateral sclerosis (ALS) appears to be a sporadic disorder in 95% of cases. Although few personal characteristics associated with developing ALS are known, identification of those at risk is essential to any vision of early intervention. There is persistent anecdotal observation that those with ALS are premorbidly physically 'fitter', although such observations are susceptible to bias. Hospital admission for coronary heart disease (CHD) might serve as an objective marke...

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Publisher copy:
10.1136/jnnp-2011-301161

Authors


Turner, MR More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Population Health
Journal:
Journal of Neurology, Neurosurgery and Psychiatry
Volume:
83
Issue:
4
Pages:
395-398
Publication date:
2012-04-05
DOI:
EISSN:
1468-330X
ISSN:
0022-3050
URN:
uuid:4c7e4394-1e3c-4e08-9dd4-0b139c7caead
Source identifiers:
321120
Local pid:
pubs:321120
Language:
English

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