Journal article icon

Journal article

The remote ischemic preconditioning stimulus modifies inflammatory gene expression in humans.

Abstract:

Remote ischemic preconditioning (IPC) reduces tissue injury caused by ischemia-reperfusion (IR) in distant organs. We tested the hypothesis that remote IPC (rIPC) modifies inflammatory gene transcription in humans. Using a microarray method, we demonstrated that a simple model of brief forearm ischemia suppresses proinflammatory gene expression in circulating leukocytes. Genes encoding key proteins involved in cytokine synthesis, leukocyte chemotaxis, adhesion and migration, exocytosis, innat...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Cardiovascular Medicine
Role:
Author
Expand authors...
Journal:
Physiological genomics
Volume:
19
Issue:
1
Pages:
143-150
Publication date:
2004-09-05
DOI:
EISSN:
1531-2267
ISSN:
1094-8341
URN:
uuid:4c661335-8fb4-499f-9484-07f624bbbf7b
Source identifiers:
105073
Local pid:
pubs:105073

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP