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The application of clinical lithotripter shock waves on RNA nucleotide delivery to cells

Abstract:

The delivery of genes into cells through the transfer of ribonucleic acids (RNAs) has been shown to cause a change in the level of target protein expression. RNA based transfection is conceptually more efficient than commonly delivered plasmid DNA because it does not require division or damage of the nuclear envelope thereby increasing the chances of the cell remaining viable. Shock waves (SWs) have been shown to induce cellular uptake by transiently altering the permeability of the plasma me...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Institution:
University of Oxford
Department:
Oxford, MPLS, Engineering Science
Role:
Author

Contributors

Institution:
University of Oxford
Department:
Oxford, MPLS, Engineering Science
Institution:
University of Oxford
Department:
Oxford, MPLS, Engineering Science
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Funding agency for:
Nwokeoha, SI
Publisher:
Elsevier Publisher's website
Journal:
Ultrasound in Medicine and Biology Journal website
Volume:
42
Issue:
10
Pages:
2478–2492
Publication date:
2016-06-05
DOI:
ISSN:
1879-291X
URN:
uuid:4c2a0611-b400-4a46-b27c-3f9f707ee51e
Source identifiers:
629457
Local pid:
pubs:629457
Paper number:
10

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