Journal article
Statins as anti-inflammatory agents in atherogenesis: molecular mechanisms and lessons from the recent clinical trials.
- Abstract:
-
Ample evidence exists in support of the potent anti-inflammatory properties of statins. In cell studies and animal models statins exert beneficial cardiovascular effects. By inhibiting intracellular isoprenoids formation, statins suppress vascular and myocardial inflammation, favorably modulate vascular and myocardial redox state and improve nitric oxide bioavailability. Randomized clinical trials have demonstrated that further to their lipid lowering effects, statins are useful in the primar...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Current pharmaceutical design More from this journal
- Volume:
- 18
- Issue:
- 11
- Pages:
- 1519-1530
- Publication date:
- 2012-01-01
- DOI:
- EISSN:
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1873-4286
- ISSN:
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1381-6128
Item Description
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:313094
- UUID:
-
uuid:4bccd5fe-0693-42b4-87da-fc94e51f792f
- Local pid:
-
pubs:313094
- Source identifiers:
-
313094
- Deposit date:
-
2012-12-19
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- Copyright date:
- 2012
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