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A mathematical model of chronic myelogenous leukemia

Abstract:

Chronic Myelogenous Leukemia (CML) is one of the most common types of leukemia. It is characterized by a chronic, seemingly stable steady state, which gives rise to oscillatory instability in the hematapoietic stem cell count. There are also many cases of CML which involve oscillations about a steady state during the chronic period (called Periodic Chronic Myelogenous Leukemia). Though instabilities are found frequently in many biological systems, it is rather unusual for the stem cell cou...

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Publication date:
2000
URN:
uuid:4bb8a627-0747-4629-a9fd-a8e542409174
Local pid:
oai:eprints.maths.ox.ac.uk:13

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