Journal article
Efficient, long term production of monocyte-derived macrophages from human pluripotent stem cells under partly-defined and fully-defined conditions
- Abstract:
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Human macrophages are specialised hosts for HIV-1, dengue virus, Leishmania and Mycobacterium tuberculosis. Yet macrophage research is hampered by lack of appropriate cell models for modelling infection by these human pathogens, because available myeloid cell lines are, by definition, not terminally differentiated like tissue macrophages. We describe here a method for deriving monocytes and macrophages from human Pluripotent Stem Cells which improves on previously published protocols in that ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 2.2MB, Terms of use)
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- Publisher copy:
- 10.1371/journal.pone.0071098
Authors
Funding
Bibliographic Details
- Publisher:
- Public Library of Science
- Journal:
- PloS one More from this journal
- Volume:
- 8
- Issue:
- 8
- Pages:
- e71098
- Publication date:
- 2013-08-12
- Acceptance date:
- 2013-06-25
- DOI:
- EISSN:
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1932-6203
- ISSN:
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1932-6203
- Pmid:
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23951090
Item Description
- Language:
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English
- Keywords:
-
- Pubs id:
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pubs:418549
- UUID:
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uuid:4b94792c-5fd8-432a-8cf0-84eefb5180f2
- Local pid:
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pubs:418549
- Source identifiers:
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418549
- Deposit date:
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2017-11-12
Terms of use
- Copyright holder:
- van Wilgenburg et al
- Copyright date:
- 2013
- Notes:
- © 2013 van Wilgenburg et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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