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SYNTHESES OF 1,5-DIDEOXY-1,5-IMINO-D-MANNITOL FROM D-MANNOSE AND FROM D-GLUCOSE

Abstract:
Unambiguous enantiospecific syntheses of 1,5-dideoxy-1,5-imino-D-mannitol (LU1, 1-deoxy-mannojirimycin) are reported (i) from D-mannose via hydrogenation of a 5-azido-5-deoxy mannose, and (ii) from D-glucose, in which the key step involves nucleophilic substitution of a trifluoromethanesulphonyl group from C-2 of D-glucose. © 1984.
Publication status:
Published

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Publisher copy:
10.1016/0040-4039(84)80058-1

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Journal:
TETRAHEDRON LETTERS More from this journal
Volume:
25
Issue:
36
Pages:
4029-4032
Publication date:
1984-01-01
DOI:
ISSN:
0040-4039


Language:
English
Pubs id:
pubs:42283
UUID:
uuid:4b2bbf41-b50d-47cc-9e51-fb180a7a89d4
Local pid:
pubs:42283
Source identifiers:
42283
Deposit date:
2012-12-19

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