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Science Forum: Donated chemical probes for open science

Abstract:

Potent, selective and broadly characterized small molecule modulators of protein function (chemical probes) are powerful research reagents. The pharmaceutical industry has generated many high-quality chemical probes and several of these have been made available to academia. However, probe-associated data and control compounds, such as inactive structurally related molecules and their associated data, are generally not accessible. The lack of data and guidance makes it difficult for researcher...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.7554/eLife.34311

Authors


Müller, S More by this author
Arrowsmith, CH More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Structural Genomics Consortium
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Structural Genomics Consortium
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Publisher:
eLife Sciences Publications Publisher's website
Journal:
eLife Journal website
Volume:
7
Pages:
Article: e34311
Publication date:
2018-04-20
Acceptance date:
2018-03-29
DOI:
ISSN:
2050-084X
Pubs id:
pubs:843883
URN:
uri:4b2277c8-ff7f-4e05-990b-6c4bb6e18845
UUID:
uuid:4b2277c8-ff7f-4e05-990b-6c4bb6e18845
Local pid:
pubs:843883

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