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Nanoparticle‐Loaded Protein–Polymer Nanodroplets for Improved Stability and Conversion Efficiency in Ultrasound Imaging and Drug Delivery

Abstract:
A new formulation of volatile nanodroplets stabilized by a protein and polymer coating and loaded with magnetic nanoparticles is developed. The droplets show enhanced stability and phase conversion efficiency upon ultrasound exposure compared with existing formulations. Magnetic targeting, encapsulation, and release of an anticancer drug are demonstrated in vitro with a 40% improvement in cytotoxicity compared with free drug.
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1002/adma.201502022

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Role:
Author
ORCID:
0000-0003-2672-2602
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Role:
Author
ORCID:
0000-0002-2094-9673
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Publisher:
Wiley Publisher's website
Journal:
Advanced Materials Journal website
Volume:
27
Issue:
37
Pages:
5484-5492
Publication date:
2015-08-11
DOI:
EISSN:
1521-4095
ISSN:
0935-9648
Pubs id:
pubs:539763
URN:
uri:4adfca43-6e26-4ace-bcce-13fc61fed164
UUID:
uuid:4adfca43-6e26-4ace-bcce-13fc61fed164
Local pid:
pubs:539763

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