Journal article
Nanoparticle‐Loaded Protein–Polymer Nanodroplets for Improved Stability and Conversion Efficiency in Ultrasound Imaging and Drug Delivery
- Abstract:
- A new formulation of volatile nanodroplets stabilized by a protein and polymer coating and loaded with magnetic nanoparticles is developed. The droplets show enhanced stability and phase conversion efficiency upon ultrasound exposure compared with existing formulations. Magnetic targeting, encapsulation, and release of an anticancer drug are demonstrated in vitro with a 40% improvement in cytotoxicity compared with free drug.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 2.3MB, Terms of use)
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- Publisher copy:
- 10.1002/adma.201502022
Authors
+ Engineering and Physical Sciences Research Council
More from this funder
- Grant:
- 1104432
- EP/L024012/1
- EP/I021795/1
+ Engineering & Physical Sciences Research Council
More from this funder
- Grant:
- EP/I021795/1
- EP/L024012/1
- Publisher:
- Wiley
- Journal:
- Advanced Materials More from this journal
- Volume:
- 27
- Issue:
- 37
- Pages:
- 5484-5492
- Publication date:
- 2015-08-11
- DOI:
- EISSN:
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1521-4095
- ISSN:
-
0935-9648
- Pmid:
-
26265592
- Language:
-
English
- Keywords:
-
- Pubs id:
-
pubs:539763
- UUID:
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uuid:4adfca43-6e26-4ace-bcce-13fc61fed164
- Local pid:
-
pubs:539763
- Source identifiers:
-
539763
- Deposit date:
-
2019-08-27
- ARK identifier:
Terms of use
- Copyright holder:
- Lee et al
- Copyright date:
- 2015
- Notes:
-
© 2015 The Authors. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Please see related dataset at https://ora.ox.ac.uk/objects/uuid:05b98b62-e045-4b06-afa4-eb73c3e4707d
- Licence:
- CC Attribution (CC BY)
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