Journal article
A high-dose 24-hour tranexamic acid infusion for the treatment of significant gastrointestinal bleeding: HALT-IT RCT
- Abstract:
-
Background Tranexamic acid reduces blood loss in surgery and the risk of death in trauma patients. Meta-analyses of small trials suggest that tranexamic acid decreases the number of deaths from gastrointestinal bleeding, but these meta-analyses are prone to selection bias.
Objective The trial provides reliable evidence of the effect of tranexamic acid on mortality, rebleeding and complications in significant acute gastrointestinal bleeding.
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Version of record, pdf, 10.0MB, Terms of use)
-
- Publisher copy:
- 10.3310/hta25580
Authors
- Publisher:
- NIHR Journals Library
- Journal:
- Health Technology Assessment More from this journal
- Volume:
- 25
- Issue:
- 58
- Publication date:
- 2021-10-19
- DOI:
- EISSN:
-
2046-4924
- ISSN:
-
1366-5278
- Pmid:
-
34663491
- Language:
-
English
- Keywords:
- Pubs id:
-
1207689
- Local pid:
-
pubs:1207689
- Deposit date:
-
2021-11-16
- ARK identifier:
Terms of use
- Copyright holder:
- Roberts et al.
- Copyright date:
- 2021
- Rights statement:
- © 2021 Roberts et al. This work was produced by Roberts et al. under the terms of a commissioning contract issued by the Secretary of State for Health and Social Care. This is an Open Access publication distributed under the terms of the Creative Commons Attribution CC BY 4.0 licence, which permits unrestricted use, distribution, reproduction and adaption in any medium and for any purpose provided that it is properly attributed. See: https://creativecommons.org/licenses/by/4.0/. For attribution the title, original author(s), the publication source –NIHR Journals Library, and the DOI of the publication must be cited.
- Licence:
- CC Attribution (CC BY)
If you are the owner of this record, you can report an update to it here: Report update to this record