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Journal article

The immunogenetics of Graves' disease

Abstract:

Graves' disease clusters in families, and higher concordance rates in monozygotic compared with dizygotic twins support a genetic basis to the disease. It seems likely that not only are a collection of small genetic effects contributing to this multifactorial complex disease but that susceptibility alleles are common in the general population and are not rare mutations. A combination of population-based case control and family-based studies is required to elucidate the genetic basis to Graves...

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Authors


Gough, SCL More by this author
Journal:
Current Opinion in Endocrinology and Diabetes
Volume:
6
Issue:
4
Pages:
270-276
Publication date:
1999
DOI:
ISSN:
1068-3097
URN:
uuid:4a2847af-f803-4123-98eb-89ee3cda40be
Source identifiers:
176300
Local pid:
pubs:176300
Language:
English

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