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Adjunctive treatments for the management of septic shock – a narrative review of the current evidence

Abstract:

Septic shock is a leading cause of death and morbidity worldwide. The cornerstones of management include prompt identification of sepsis, early initiation of antibiotic therapy, adequate fluid resuscitation and organ support. Over the past two decades, there have been considerable improvements in our understanding of the pathophysiology of sepsis and the host response, including regulation of inflammation, endothelial disruption and impaired immunity. This has offered opportunities for innova...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1111/anae.15369

Authors


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Role:
Author
ORCID:
0000-0003-3043-446X
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Institution:
University of Oxford
Role:
Author
Publisher:
Wiley Publisher's website
Journal:
Anaesthesia Journal website
Article number:
anae.15369
Publication date:
2021-01-09
DOI:
EISSN:
1365-2044
ISSN:
0003-2409
Pubs id:
1156298
Local pid:
pubs:1156298
Language:
English
Keywords:

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