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Acquisition of siderophores in gram-negative bacteria.

Abstract:

The outer membrane of Gram-negative bacteria constitutes a permeability barrier that protects the cell from exterior hazards, but also complicates the uptake of nutrients. In the case of iron, the challenge is even greater, because of the scarcity of this indispensable element in the cell's surroundings. To solve this dilemma, bacteria have evolved sophisticated mechanisms whereby the concerted actions of receptor, transporter and energy-transducing proteins ensure that there is a sufficient ...

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Publication status:
Published

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Publisher copy:
10.1038/nrm1015

Authors


Faraldo-Gómez, JD More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Journal:
Nature reviews. Molecular cell biology
Volume:
4
Issue:
2
Pages:
105-116
Publication date:
2003-02-05
DOI:
EISSN:
1471-0080
ISSN:
1471-0072
URN:
uuid:49536d23-20ce-4c87-af91-896589fa0560
Source identifiers:
100509
Local pid:
pubs:100509

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