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Nanocrystallography measurements of early stage synthetic malaria pigment

Abstract:

The recent availability of extremely intense, femtosecond X-ray free-electron laser (XFEL) sources has spurred the development of serial femtosecond nanocrystallography (SFX). Here, SFX is used to analyze nanoscale crystals of β-hematin, the synthetic form of hemozoin which is a waste by-product of the malaria parasite. This analysis reveals significant differences in β-hematin data collected during SFX and synchrotron crystallography experiments. To interpret these differences two possibilit...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1107/S1600576717012663

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Role:
Author
ORCID:
0000-0002-2392-9942
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Publisher:
International Union of Crystallography Publisher's website
Journal:
Journal of applied crystallography Journal website
Volume:
50
Issue:
Pt 5
Pages:
1533-1540
Publication date:
2017-09-28
Acceptance date:
2017-09-04
DOI:
EISSN:
1600-5767
ISSN:
0021-8898
Pubs id:
pubs:905621
URN:
uri:4898b9eb-53ff-43e3-98e8-6a51353161b7
UUID:
uuid:4898b9eb-53ff-43e3-98e8-6a51353161b7
Local pid:
pubs:905621

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