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Journal article

Long-acting inhaled anticholinergic therapy improves sleeping oxygen saturation in COPD.

Abstract:

Oxygen desaturation occurs during sleep in severe chronic obstructive pulmonary disease (COPD), especially during rapid eye movement (REM) sleep, due to hypoventilation and ventilation-perfusion mismatching, but the possible contribution of airflow limitation is unclear. In a randomised, placebo-controlled, double-blind study of severe, stable COPD patients, the authors compared 4 weeks treatment with a long-acting inhaled anticholinergic agent (tiotropium), taken in the morning (tiotropium-A...

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Journal:
The European respiratory journal
Volume:
23
Issue:
6
Pages:
825-831
Publication date:
2004-06-05
DOI:
EISSN:
1399-3003
ISSN:
0903-1936
URN:
uuid:48203b8d-f50e-471e-8601-202d1c2c0dbe
Source identifiers:
94132
Local pid:
pubs:94132

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