Journal article
Disease severity and effective parasite multiplication rate in falciparum aalaria.
- Abstract:
- Patients presenting with severe falciparum malaria in a Bangladeshi tertiary hospital had higher total parasite burden, estimated by parasitemia and plasma PfHRP2, than uncomplicated malaria patients despite shorter fever duration. This suggests that higher parasite multiplication rates (PMR) contribute to causing the higher biomass found in severe disease. Compared with patients without a history of previous malaria, patients with previous malaria carried a lower parasite biomass with similar fever duration at presentation, suggesting that host immunity reduces the PMR.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 255.5KB, Terms of use)
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- Publisher copy:
- 10.1093/ofid/ofx169
Authors
- Publisher:
- Oxford University Press
- Journal:
- Open Forum Infectious Diseases More from this journal
- Volume:
- 4
- Issue:
- 4
- Pages:
- ofx169
- Publication date:
- 2017-12-01
- Acceptance date:
- 2017-11-18
- DOI:
- EISSN:
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2328-8957
- Pmid:
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29302604
- Language:
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English
- Keywords:
- Pubs id:
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pubs:817676
- UUID:
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uuid:4819d8ed-73e5-4275-9c92-242fdfd50fdc
- Local pid:
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pubs:817676
- Source identifiers:
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817676
- Deposit date:
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2018-01-16
- ARK identifier:
Terms of use
- Copyright holder:
- White et al
- Copyright date:
- 2017
- Notes:
- © The Author(s) 2017. Published by Oxford University Press on behalf of Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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