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Safety of the insect repellent N,N-diethyl-M-toluamide (DEET) in pregnancy.

Abstract:

The safety of daily application of N, N-diethyl-m-toluamide (DEET) (1.7 g of DEET/day) in the second and third trimesters of pregnancy was assessed as part of a double-blind, randomized, therapeutic trial of insect repellents for the prevention of malaria in pregnancy (n = 897). No adverse neurologic, gastrointestinal, or dermatologic effects were observed for women who applied a median total dose of 214.2 g of DEET per pregnancy (range = 0-345.1 g). DEET crossed the placenta and was detected...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Hamilton, KA More by this author
Simpson, JA More by this author
Luxemburger, C More by this author
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Journal:
The American journal of tropical medicine and hygiene
Volume:
65
Issue:
4
Pages:
285-289
Publication date:
2001-10-05
EISSN:
1476-1645
ISSN:
0002-9637
URN:
uuid:47d4a590-a4a2-4b8a-a9a8-961d4f3b4405
Source identifiers:
28460
Local pid:
pubs:28460

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