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The creatine kinase energy transport system in the failing mouse heart.

Abstract:

Characteristic alterations of the creatine kinase (CK) system occur in heart failure and may contribute to contractile dysfunction. We examined two mouse models of chronic cardiac stress, transverse aortic constriction (TAC) and coronary artery ligation (CAL), and examined the relationship of CK system changes with hypertrophy and heart failure development. C57Bl/6 mice were subjected to TAC or sham surgery and sacrificed after 2-10 weeks according to echocardiographic criteria of myocardial ...

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Publication status:
Published

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Publisher copy:
10.1016/j.yjmcc.2007.03.899

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
Journal:
Journal of molecular and cellular cardiology
Volume:
42
Issue:
6
Pages:
1129-1136
Publication date:
2007-06-01
DOI:
EISSN:
1095-8584
ISSN:
0022-2828
Source identifiers:
104868
Language:
English
Keywords:
Pubs id:
pubs:104868
UUID:
uuid:47d193a0-955c-4516-a48c-6cbb2e9e5985
Local pid:
pubs:104868
Deposit date:
2012-12-19

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