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What is cooperativity?

Abstract:
The lamprey holds the clue to the link between supramolecular self-assembly and allosteric ligand binding. Chelate cooperativity in self-assembled structures results in denaturation behavior that is indistinguishable from allosteric ligand binding. The chelate effect is the most common origin of positive cooperativity, yet its significance has been widely overlooked. © 2009 Wiley-VCH Verlag GmbH and Co. KGaA.
Publication status:
Published

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Publisher copy:
10.1002/anie.200902490

Authors

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author


Journal:
Angewandte Chemie (International ed. in English) More from this journal
Volume:
48
Issue:
41
Pages:
7488-7499
Publication date:
2009-01-01
DOI:
EISSN:
1521-3773
ISSN:
1433-7851


Language:
English
Keywords:
Pubs id:
pubs:51860
UUID:
uuid:47c48981-ea35-48a6-9c41-f41fe6c87c0b
Local pid:
pubs:51860
Source identifiers:
51860
Deposit date:
2012-12-19
ARK identifier:

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