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Journal article : Review

Characterising biomolecular interactions and dynamics with mass photometry

Abstract:

We review recent advances in our ability to characterise biomolecular structure, interactions and associated dynamics by mass photometry (MP), the label-free detection and mass measurement of individual biomolecules in solution. Molecular counting and identification provides direct access to relative abundance, and thereby affinities, while associated dynamics yield on- and off-rates. The molecular resolution afforded by MP enables these measurements as a function of stoichiometry and assembl...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Physical & Theoretical Chem
Oxford college:
Exeter College
Role:
Author
ORCID:
0000-0003-0136-7704
Publisher:
Elsevier
Journal:
Current Opinion in Chemical Biology More from this journal
Volume:
68
Article number:
102132
Publication date:
2022-04-08
Acceptance date:
2022-02-22
DOI:
ISSN:
1367-5931
Language:
English
Keywords:
Subtype:
Review
Pubs id:
1250796
Local pid:
pubs:1250796
Deposit date:
2022-05-04

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