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Evaluation of the frailty characteristics and clinical outcomes according to the new frailty-based outcome prediction model (Myeloma Risk Profile-MRP) in a UK real-world cohort of elderly newly diagnosed Myeloma patients

Abstract:

The management of myeloma in the elderly is shifting its focus towards reducing the risk of under-treating fit patients and the risk of over-treating frail patients. Frailty assessment is required in this patient group in order to individualise treatment decisions. In addition to the proven prognostic values of the International Myeloma Working Group (IMWG) frailty score and the revised Myeloma Co-morbidity Index (R-MCI), a new easy-to-use frailty-based risk profile score (high-risk (i.e. fra...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0262388

Authors

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Institution:
University of Oxford
Role:
Author
ORCID:
0000-0001-9578-7632
More by this author
Institution:
University of Oxford
Role:
Author
ORCID:
0000-0002-2681-5860
More by this author
Role:
Author
ORCID:
0000-0002-3748-6142
More by this author
Institution:
University of Oxford
Role:
Author
More by this author
Institution:
University of Oxford
Role:
Author
ORCID:
0000-0001-8725-4422


Publisher:
Public Library of Science
Journal:
PLoS ONE More from this journal
Volume:
17
Issue:
1
Pages:
e0262388-e0262388
Publication date:
2022-01-11
DOI:
EISSN:
1932-6203
ISSN:
1932-6203


Language:
English
Keywords:
Pubs id:
1231819
Local pid:
pubs:1231819
Source identifiers:
W4206649514
Deposit date:
2026-04-09
ARK identifier:
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