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Thesis

The sequence and characterisation of ?-globin haplotypes in human populations

Abstract:

Genetic variation at the human a-globin gene complex has only been characterised to date as haplotypes - a linked set of 7 RFLPs and 2 VNTRs - and not at the sequence level. However, an understanding of the extent of sequence variability at this locus, and its relation to underlying mutational processes, is of interest to studies of both molecular and population genetics.

This variation has been investigated by the deve...

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Peer review status:
Peer Reviewed

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Department:
University of Oxford
This thesis was digitised thanks to the generosity of Dr Leonard Polonsky More from this funder
Publication date:
1996
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Local pid:
polonsky:4:49

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