Journal article icon

Journal article

Molecular genetic studies of sporadic pituitary tumors.

Abstract:

Tumor formation may result from the activation of dominant oncogenes or by inactivation of recessive, tumor suppressor genes. The role of such mutations in the development of pituitary tumors has been studied. Tumors from 88 patients, representing the 4 major classes of adenoma, were investigated. In DNA extracted from matched leukocyte and tumor samples, allelic deletions were sought with 15 probes identifying restriction fragment length polymorphisms on chromosomes 1, 5, 10, 11, 13, 17, 20,...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1210/jc.78.2.387

Authors


Expand authors...
Journal:
The Journal of clinical endocrinology and metabolism
Volume:
78
Issue:
2
Pages:
387-392
Publication date:
1994-02-05
DOI:
EISSN:
1945-7197
ISSN:
0021-972X
URN:
uuid:46df2c00-fee3-4bd6-abc5-b141dd0c78b8
Source identifiers:
20468
Local pid:
pubs:20468

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP