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Serial QuantiFERON testing and tuberculosis disease risk among young children: an observational cohort study

Abstract:

BACKGROUND: The value of quantitative interferon-γ release assay results for predicting progression from Mycobacterium tuberculosis infection to active disease is unknown. We aimed to investigate the relation between QuantiFERON-TB Gold In-Tube (QFT) conversion interferon-γ values and risk of subsequent active tuberculosis disease and of QFT reversion.

METHODS: We analysed data from a reported vaccine efficacy trial of the tuberculosis vaccine MVA85A in South Africa. QFT negative, H...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/S2213-2600(17)30060-7

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Publisher:
Elsevier
Journal:
Lancet Respiratory Medicine More from this journal
Volume:
5
Issue:
4
Pages:
282-290
Publication date:
2017-02-16
Acceptance date:
2016-12-19
DOI:
EISSN:
2213-2619
ISSN:
2213-2600


Language:
English
Keywords:
Pubs id:
pubs:681918
UUID:
uuid:46c8d0f5-6f1c-4f0f-b10f-ea82f468bd36
Local pid:
pubs:681918
Source identifiers:
681918
Deposit date:
2017-03-29
ARK identifier:

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