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Immunohistochemical demonstration of p24 HTLV III major core protein in different cell types within lymph nodes from patients with lymphadenopathy syndrome (LAS).

Abstract:

The p24 protein is the major core protein of LAV/HTLV III which is the putative agent of the lymphadenopathy syndrome. By the use of an anti-p24 monoclonal antibody we have studied the presence of LAV/HTLV III infected cells in 20 lymph nodes obtained from lymphadenopathy syndrome patients: 14 lymph nodes were characterized by prominent follicular hyperplasia consistent with the early phase of the syndrome and six lymph nodes presented marked regressive changes. Cells positive for p24 were de...

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Clinical Lab Sciences
Role:
Author
Journal:
Histopathology
Volume:
10
Issue:
1
Pages:
5-13
Publication date:
1986-01-05
DOI:
EISSN:
1365-2559
ISSN:
0309-0167
URN:
uuid:46984837-cd4a-4fdc-a10c-dd8647b139e7
Source identifiers:
486754
Local pid:
pubs:486754

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