Patent
Use of iminosugar derivatives to inhibit ion channel activity
- Alternative title:
- World Intellectual Property Ogranization patent WO/2004/047719
- Documentation:
- Disclosed are methods and kits to treat HCV infection by administering an iminosugar derivative compound that is effective to inhibit the activity of HCV p7 protein, and methods by which to screen for compounds that inhibit the activity of p7 protein or variants thereof. The disclosed N-substituted imino compounds, and pharmaceutical compositions thereof, inhibit the capability of HCV p7 to permeabilize membranes. Particularly efficacious compounds are imino sugars derived from N-alkylated piperidines. Also disclosed are methods for screening for potential HCV antiviral agents.
- Publication status:
- Published
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- Files:
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(Preview, Version of record, pdf, 1.9MB, Terms of use)
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Authors
- Publisher:
- World Intellectual Property Ogranization
- Publication date:
- 2004-06-10
- Patent number:
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WO2004047719
- Application number:
- PCT/IB2003/006471
- Patent status:
- Issued/granted
- Pubs id:
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pubs:383431
- UUID:
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uuid:46909b18-f58f-4e1f-8025-042725e482eb
- Local pid:
-
pubs:383431
- Source identifiers:
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383431
- Deposit date:
-
2016-02-11
- ARK identifier:
Terms of use
- Copyright date:
- 2004
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