Journal article
Dynamic shear analysis: a novel method to determine mechanical integrity of normal and torn human acetabular labra. Implications for prediction of outcome of repair
- Abstract:
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Objectives: The aim of this study was to investigate the structural integrity of torn and non-torn human acetabular labral tissue.
Methods: A total of 47 human labral specimens were obtained from a biobank. These included 22 torn specimens and 25 control specimens from patients undergoing total hip arthroplasty with macroscopically normal labra. The specimens underwent dynamic shear analysis using a rheometer to measure storage modulus, as an indicator of structural integrity.
Results: There was a significant difference in the storage modulus between torn (mean modulus = 2144.08 Pa) and non-torn (3178.1 Pa) labra (p = 0.0001).
Conclusion: The acetabular labrum of young patients with a tear has significantly reduced structural integrity compared with a non-torn labrum in older patients with end-stage osteoarthritis. This study contributes to the understanding of the biomechanics of labral tears, and the observation of reduced structural integrity in torn labra may explain why some repairs fail. Our data demonstrate that labral tears probably have a relatively narrow phenotype, presenting a basis for further investigations that will provide quantifiable data to support their classification and a means to develop a standardized surgical technique for their repair. This study also demonstrates the value of novel biomechanical testing methods in investigating pathological tissues of orthopaedic interest.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 883.5KB, Terms of use)
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- Publisher copy:
- 10.1302/2046-3758.77.BJR-2017-0282.R2
Authors
- Publisher:
- British Editorial Society of Bone and Joint Surgery
- Journal:
- Bone and Joint Research More from this journal
- Volume:
- 7
- Issue:
- 7
- Pages:
- 440-446
- Publication date:
- 2018-07-06
- Acceptance date:
- 2018-04-30
- DOI:
- EISSN:
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2046-3758
- Keywords:
- Pubs id:
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pubs:847853
- UUID:
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uuid:45fcbceb-7a69-4e00-9042-8962be1cac02
- Local pid:
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pubs:847853
- Source identifiers:
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847853
- Deposit date:
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2018-05-16
Terms of use
- Copyright holder:
- © 2018 Woods, et al
- Copyright date:
- 2018
- Notes:
- This is an open-access article distributed under the terms of the Creative Commons Attributions licence (CC-BY-NC), which permits unrestricted use, distribution, and reproduction in any medium, but not for commercial gain, provided the original author and source are credited.
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