Targeting the subthalamic nucleus.

Journal article

The small size and surrounding neuronal structures and fibre tracts make the STN a difficult stereotactic target. In this article we present the technique used by us to target the STN. Our combined experience from two centres comprises 18 lesions and 27 stimulator implants in the STN. Our criteria for patient selection and the use of MRI, frame-on CT and volumetric image fusion are presented. The role of a movement disorder specialist neurologist in the operating theatre, local field potential recording, impedance monitoring, macrostimulation, post-operative CT/MRI and test stimulation are detailed.

Authors: Aziz, T; Nandi, D; Parkin, S; Liu, X; Giladi, N

• Publication status: Published
• Journal: Stereotactic and functional neurosurgery
• Volume: 77
• Issue: 1-4
• Pages: 87-90
• Publication date: 2001-01-01
• DOI: 10.1159/000064602
• EISSN: 1423-0372
• ISSN: 1011-6125
• Language: English
• Keywords: Electrocoagulation; Parkinson Disease; Electric Stimulation Therapy; Tomography, X-Ray Computed; Image Processing, Computer-Assisted; Monitoring, Intraoperative; Electrodes, Implanted; Retrospective Studies; Magnetic Resonance Imaging; Recurrence; Subthalamic Nucleus; Stereotaxic Techniques; Humans; Treatment Outcome