Amperometric detection of glucose using self-catalytic carbon paste electrodes.

Journal article

The analytical detection of d-glucose by means of self-catalytic carbon paste electrodes is described. In the construction of these electrodes, carbon powder has been modified with the redox liquid n-butylferrocene, which simultaneously serves both to help bind the paste together whilst also acting as a mediator in the enzymatic oxidation of d-glucose by glucose oxidase. The sensor then functions by monitoring the electrochemical oxidation of the constituent n-butylferrocene itself. Through testing in model glucose solutions, the electrodes were found to yield a linear response over a d-glucose concentration range of 2-20 mM. They were also successfully employed in the determination of d-glucose levels in a spiked blood sample, giving a detection limit of 0.8 mM (based on the 3sigma criterion).

Authors: Evans, R; Banks, C; Compton, R

• Publication status: Published
• Journal: Analyst
• Volume: 129
• Issue: 5
• Pages: 428-431
• Publication date: 2004-05-01
• DOI: 10.1039/b402091j
• EISSN: 1364-5528
• ISSN: 0003-2654
• Language: English
• Keywords: Animals; Horses; Carbon; Electrodes; Biological Markers; Electrochemistry; Blood Glucose