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HLA-A alleles differentially associate with severity to Plasmodium falciparum malaria infection in Ibadan, Nigeria

Abstract:

Human Leukocyte Antigen (HLA), particularly HLA-B and class II alleles have been differentially associated with disease outcomes in different populations following infection with the malaria Plasmodium falciparum. However, the effect of HLA-A on malaria infection and/or disease is not fully understood. Recently, HLA-A alleles have been suggested to play a role in the outcome of P. falciparum malaria infection in a Malian study. Herein, we investigated the association between HLA-A alleles and...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Authors


Ademola, SA More by this author
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Target Discovery Institute
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Grant:
LSHP-CT-2004-503578 and Seventh Framework Programme (FP7/2007-2013) under grant agreement N° 242095
Publisher:
Ibadan Biomedical Communications Group Publisher's website
Journal:
African Journal of Biomedical Research Journal website
Volume:
20
Issue:
3
Pages:
223-228
Publication date:
2017-11-26
Acceptance date:
2017-09-30
ISSN:
1119-5096
Pubs id:
pubs:821111
URN:
uri:4520e376-c17c-4034-9e84-10b4bd0493cb
UUID:
uuid:4520e376-c17c-4034-9e84-10b4bd0493cb
Local pid:
pubs:821111

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