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Journal article

Stable and unstable malaria hotspots in longitudinal cohort studies in Kenya

Abstract:

Background: Infectious diseases often demonstrate heterogeneity of transmission among host populations. This heterogeneity reduces the efficacy of control strategies, but also implies that focusing control strategies on "hotspots" of transmission could be highly effective. Methods and findings: In order to identify hotspots of malaria transmission, we analysed longitudinal data on febrile malaria episodes, asymptomatic parasitaemia, and antibody titres over 12 y from 256 homesteads in three s...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pmed.1000304

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Institution:
"Kilifi KEMRI- Wellcome Trust Collaborative Research Programme, Centre for Geographic Medicine Research - Coast, Kilifi, Kenya", "University of Oxford"
Department:
Medical Sciences Division - Clinical Vaccinology and Tropical Medicine,Centre for (CCVTM)
Role:
Author
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Institution:
"Kilifi KEMRI- Wellcome Trust Collaborative Research Programme, Centre for Geographic Medicine Research - Coast, Kilifi, Kenya", "University of Oxford"
Department:
Medical Sciences Division - Clinical Vaccinology and Tropical Medicine,Centre for (CCVTM)
Role:
Author
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Institution:
Karolinska Instututet, Stockholm, Sweden
Department:
Department of Medicine Solna
Role:
Author
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Institution:
"University of Oxford", "Centre for Geographic Medicine Research - Coast, Kenya Medical Research Institute/Wellcome Trust Research Programme, Nairobi, Kenya"
Department:
Malaria Public Health & Epidemiology Group
Role:
Author
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Institution:
Kilifi KEMRI- Wellcome Trust Collaborative Research Programme, Centre for Geographic Medicine Research - Coast, Kilifi, Kenya
Role:
Author
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Funding agency for:
Osier, F
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Funding agency for:
Hay, S
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Funding agency for:
Marsh, K
Wellcome Trust More from this funder
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Funding agency for:
Bejon, P
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Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Medicine Journal website
Volume:
7
Issue:
7
Article number:
e1000304
Publication date:
2010-07-01
DOI:
EISSN:
1549-1676
ISSN:
1549-1277
Language:
English
Keywords:
Subjects:
UUID:
uuid:43ff9034-5504-446c-96f3-cdf813444bb3
Local pid:
ora:4115
Deposit date:
2010-08-31

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