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Journal article

Progress in DNA-based heterologous prime-boost immunization strategies for malaria.

Abstract:

An effective vaccine against malaria is urgently required to relieve the immense human suffering and mortality caused by this parasite. A successful subunit vaccine against the liver stage of malaria will require the induction of high levels of protective T cells. Despite success in small animal models, DNA vaccines fail to induce strong cellular immune responses in humans. However, DNA vaccines can induce a T-cell response that can be strongly boosted by recombinant viral vectors. We have ev...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Jenner Institute
Role:
Author
Journal:
Immunological reviews
Volume:
199
Issue:
1
Pages:
126-143
Publication date:
2004-06-01
DOI:
EISSN:
1600-065X
ISSN:
0105-2896
Source identifiers:
95345
Language:
English
Keywords:
Pubs id:
pubs:95345
UUID:
uuid:43c90b26-6b02-41a4-9825-d4088ffb0069
Local pid:
pubs:95345
Deposit date:
2012-12-19

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