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Cardiotoxicity of antimalarial drugs.

Abstract:

There are consistent differences in cardiovascular state between acute illness in malaria and recovery that prolong the electrocardiographic QT interval and have been misinterpreted as resulting from antimalarial cardiotoxicity. Of the different classes of antimalarial drugs, only the quinolines, and structurally related antimalarial drugs, have clinically significant cardiovascular effects. Drugs in this class can exacerbate malaria-associated orthostatic hypotension and several have been sh...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Role:
Author
Journal:
The Lancet. Infectious diseases
Volume:
7
Issue:
8
Pages:
549-558
Publication date:
2007-08-05
DOI:
EISSN:
1474-4457
ISSN:
1473-3099
URN:
uuid:43812b2c-d846-44e2-8663-86db5cbdab4c
Source identifiers:
40417
Local pid:
pubs:40417

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