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The Listeria transcriptional landscape from saprophytism to virulence.

Abstract:

The bacterium Listeria monocytogenes is ubiquitous in the environment and can lead to severe food-borne infections. It has recently emerged as a multifaceted model in pathogenesis. However, how this bacterium switches from a saprophyte to a pathogen is largely unknown. Here, using tiling arrays and RNAs from wild-type and mutant bacteria grown in vitro, ex vivo and in vivo, we have analysed the transcription of its entire genome. We provide the complete Listeria operon map and have uncovered ...

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Publisher copy:
10.1038/nature08080

Authors


Toledo-Arana, A More by this author
Dussurget, O More by this author
Nikitas, G More by this author
Guet-Revillet, H More by this author
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Journal:
Nature
Volume:
459
Issue:
7249
Pages:
950-956
Publication date:
2009-06-05
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
URN:
uuid:433c4b63-43a6-41bf-9799-4ae971dce1e0
Source identifiers:
252400
Local pid:
pubs:252400

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