Using optical stimulation to study the developing thalamocortical circuit in mouse somatosensory cortex

Thesis

Charting connectivity between neurons in the brain is one of the main goals of circuit neuroscience. Despite great advances in our understanding of cortical circuit organisation, comparatively little attention has been devoted to studying how the intricate cortical connectivity emerges. Current views are that early synaptic connectivity within the cortex and between thalamus and cortex is largely mediated via silent synapses. Early patterns of network activity synchronise firing in pre- an...

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Authors: Marques-Smith, A

• Publication date: 2014
• DOI: 10.5287/ora-kojegzn2j
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Keywords: neurobiology; interneurons; subplate; Martinotti
• Subjects: Biology; Physiology and anatomy